An Examination of Cobalt(II) Porphyrin: Electrochemical Properties, Reduction Characteristics, DFT Calculations, and Molecular Docking With α-Glucosidase

Ijaz Ullah Muzaddadi, Bondana Kalita, Marappan Velusamy, et al. International Journal of Electrochemistry, 2026, 2026:1998719. DOI: 10.1155/ijel/1998719

Electrochemical studies of cobalt(II) meso-tetrakis(3,4,5-trimethoxyphenyl)porphyrin [Co^II(T(3,4,5-OCH₃)PP)] were conducted using the cyclic voltammetry technique. UV-Vis and EPR were used to investigate the reduction properties of [Co^II(T(3,4,5-OCH₃) PP)]. The CV data show that [Co^II(T(3,4,5-OCH₃)PP)] is reduced to [Co^I(T(3,4,5-OCH3)PP)] and then reacts with dichloromethane to form [Co^III(T(3,4,5-OCH₃)PP)]. This occurs due to electrosynthesis establishing a σ bond between the cobalt atoms and the carbon atoms in the meso position of the porphyrin.

This work is available in https://doi.org/10.1155/ijel/1998719